Richard D Minshall Selected Research

Caveolin 1

1/2022	Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.
10/2019	Depletion of Caveolin-1 in Type 2 Diabetes Model Induces Alzheimer's Disease Pathology Precursors.
5/2017	Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension.
3/2017	Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension.
1/2017	Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling.
1/2016	Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis.
8/2014	Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase.
1/2014	Ropivacaine attenuates endotoxin plus hyperinflation-mediated acute lung injury via inhibition of early-onset Src-dependent signaling.
12/2013	Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation.
12/2013	Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension.

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Richard D Minshall Research Topics

Disease

19	Inflammation (Inflammations) 10/2021 - 04/2002
12	Sepsis (Septicemia) 12/2019 - 04/2002
10	Edema (Dropsy) 01/2022 - 11/2007
10	Lung Injury 01/2021 - 04/2005
8	Vascular Remodeling 01/2019 - 05/2008
7	Pneumonia (Pneumonitis) 05/2015 - 02/2008
6	Neoplasms (Cancer) 01/2022 - 02/2007
6	Ventilator-Induced Lung Injury 10/2021 - 08/2011
6	Pulmonary Hypertension 01/2021 - 05/2008
6	Acute Lung Injury 10/2020 - 04/2005
4	Hypoxia (Hypoxemia) 04/2019 - 01/2015
4	Vascular System Injuries 01/2019 - 04/2002
4	Pulmonary Edema 01/2014 - 04/2005
3	Familial Primary Pulmonary Hypertension 05/2017 - 12/2013
2	Breast Neoplasms (Breast Cancer) 01/2021 - 02/2007
2	Obesity 10/2020 - 11/2009
2	Type 2 Diabetes Mellitus (MODY) 10/2020 - 10/2019
2	Pulmonary Arterial Hypertension 01/2019 - 09/2010
2	Vascular Diseases (Vascular Disease) 01/2019 - 01/2018
2	Fibrosis (Cirrhosis) 01/2012 - 12/2003
2	Lung Diseases (Lung Disease) 01/2012 - 09/2010
2	Ischemia 11/2007 - 04/2005
1	Hemolytic Anemia 01/2022
1	Sickle Cell Anemia (Hemoglobin S Disease) 01/2022
1	Triple Negative Breast Neoplasms 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 10/2021
1	Insulin Resistance 10/2020
1	Wounds and Injuries (Trauma) 01/2020
1	Endotoxemia 12/2019
1	Alzheimer Disease (Alzheimer's Disease) 10/2019
1	Memory Disorders (Memory Loss) 10/2019
1	Dementia (Dementias) 01/2019
1	Dyslipidemias (Dyslipidemia) 01/2018

Drug/Important Bio-Agent (IBA)

18	Caveolin 1IBA 01/2022 - 12/2003
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2002
9	EndotoxinsIBA 10/2020 - 11/2007
7	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2016 - 04/2005
5	LipopolysaccharidesIBA 12/2019 - 01/2010
5	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 12/2017 - 06/2011
5	Anesthetics (Anesthetic Agents)IBA 02/2015 - 04/2005
4	Peptides (Polypeptides)IBA 01/2020 - 05/2010
4	AlbuminsIBA 10/2012 - 01/2008
3	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2012
3	CytokinesIBA 12/2019 - 09/2015
3	Sevoflurane (Ultane)FDA LinkGeneric 12/2019 - 01/2013
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2015
3	Propofol (Diprivan)FDA LinkGeneric 02/2015 - 04/2005
3	LipidsIBA 11/2009 - 11/2007
2	Adenosine Triphosphate (ATP)IBA 01/2021 - 10/2017
2	AntioxidantsIBA 01/2021 - 04/2005
2	Blood Proteins (Serum Proteins)IBA 10/2020 - 01/2008
2	Thrombin FDA Link 01/2020 - 10/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2019 - 09/2012
2	Oxidants (Oxidizing Agents)IBA 01/2018 - 09/2009
2	EnzymesIBA 01/2018 - 09/2010
2	Adenine FDA LinkGeneric 05/2017 - 03/2017
2	Vasoconstrictor AgentsIBA 01/2016 - 05/2008
2	Ropivacaine (Naropin)FDA LinkGeneric 01/2014 - 09/2012
2	Liposomes (Liposome)IBA 10/2012 - 04/2002
2	Complementary DNA (cDNA)IBA 10/2012 - 04/2002
1	GBT1118IBA 01/2022
1	Tyrosine (L-Tyrosine)FDA Link 01/2022
1	ThrombomodulinIBA 01/2022
1	cadherin 5IBA 01/2021
1	CateninsIBA 01/2021
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2021
1	Evans Blue (Blue, Evans)FDA Link 01/2021
1	Potassium Channels (Potassium Channel)IBA 01/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	Leptin ReceptorsIBA 10/2020
1	Insulin-Like PeptidesIBA 10/2020
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2020
1	Peptide Hydrolases (Proteases)FDA Link 01/2020
1	Interleukin-4 (Interleukin 4)IBA 01/2020
1	Ketamine FDA LinkGeneric 12/2019
1	Xylazine (Xylazin)IBA 12/2019
1	Amyloid (Amyloid Fibrils)IBA 10/2019
1	MonocrotalineIBA 04/2019
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2019
1	InflammasomesIBA 01/2019
1	Interleukin-18 (Interleukin 18)IBA 01/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2019
1	Semaxinib (SU5416)IBA 01/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019
1	oxidized low density lipoproteinIBA 01/2018
1	Peroxidase (Myeloperoxidase)IBA 12/2017
1	Purinergic P2X7 ReceptorsIBA 10/2017
1	Adenosine (Adenocard)FDA LinkGeneric 10/2017
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 10/2017
1	FructoseIBA 01/2017
1	Monomeric GTP-Binding ProteinsIBA 01/2017

Therapy/Procedure

4	Therapeutics 01/2022 - 10/2014
4	Artificial Respiration (Mechanical Ventilation) 10/2021 - 02/2012
4	Punctures 01/2019 - 01/2013
4	Ligation 01/2019 - 01/2013
2	Resuscitation 02/2015 - 03/2009
1	Topical Administration 01/2020
1	Anesthesia 12/2019
1	Transplantation 01/2019